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Overview
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The HPV (33) Luciferase Pseudotyped Virus is packaged with the L1 (P06416) and L2 (P06418) proteins, and contains the firefly luciferase gene. This pseudovirus is replication-defective, meaning it cannot produce new virus particles after infection. It can effectively infect the HEK-293T SV40gp6 (HEK-293TT) cell line, which overexpresses the SV40 Large T antigen. This virus can be used for neutralizing antibody titer determination, inhibitor screening, viral entry studies, and HPV vaccine development.
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Overview