Name: HOXA9 Recombinant Protein
Price: Inquiry

- Overview
  - HOXA9 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 295 amino acids (1-272) and having a molecular mass of 32.6 kDa. HOXA9 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Homeobox A9 (HOXA9) is a member of the Abd-B homeobox family. The HOXA9 protein is a transcription factor with a key role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a distinctive feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. HOXA9 overexpression noticeably expands hematopoietic stem cells. The HOXA9 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which regulates gene expression, morphogenesis, and differentiation. HOXA9 is a sequence-specific transcription factor which is part of a developmental regulatory system, which provides cells with specific positional identities on the anterior-posterior axis. HOXA9 is essential for induction of E-selectin and VCAM-1, on the endothelial cells surface at sites of inflammation.
    
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- Properties
  - Protein Name
    
    Homeobox A9, HOX1G, Homeobox Protein Hox-1G, Homeodomain Protein HOXA9, Homeobox Protein Hox-A9, Homeo Box A9, HOX1.7, ABD-B, HOX1, HOXA9.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    The HOXA9 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

HOXA9 Recombinant Protein

HOXA9 Recombinant Protein

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