HMGB2 Recombinant Protein

HMGB2 Recombinant Protein

Catalog Number:
P001415266ABE
Mfr. No.:
Abe32-3974
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • HMGB2 Human Recombinant produced in Baculovirus is a single polypeptide chain containing 232 amino acids (1-209) and having a molecular mass of 26.4 kDa. The HMGB2 is fused to a 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. HMGB2 belongs to the non-histone chromosomal high-mobility group protein family which are chromatin-associated and highly spread in the nucleus of higher eukaryotic cells. HMGB2 can successfully bend DNA and form DNA circles which indicates that HMGB2 facilitates cooperative interactions between cis-acting proteins by promoting DNA flexibility. Additionally, HMGB2 takes part in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

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      • Properties
        • Protein Name
          High mobility group (nonhistone chromosomal) protein B2, h mobility group box 2, HMG2.
          Source
          Baculovirus
          Type
          Recombinant Proteins
          Purification
          Greater than 90% as determined by SDS-PAGE.
          Formulation
          The HMGB2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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