HMGN3 Recombinant Protein

HMGN3 Recombinant Protein

Catalog Number:
P001415269ABE
Mfr. No.:
Abe32-3977
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • HMGN3 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 100 amino acids (1-77 a.a) andhaving a molecular mass of 10.8 kDa. HMGN3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. High Mobility Group Nucleosomal Binding Domain 3 (HMGN3), binds thyroidhormone receptor beta, however it occurs only in the presence of thyroidhormone. Thyroid hormone receptors are hormone-dependent transcription factorswhich regulate expression of a variety of particular target genes. HMGN3 is considered to reduce the compactnessof the chromatin fiber in nucleosomes, in that way enhancing transcription fromchromatin templates.

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      • Properties
        • Protein Name
          High Mobility Group Nucleosomal Binding Domain 3, TRIP7, TR-Interacting Protein 7, High Mobility Group Nucleosome-BindingDomain-Containing Protein 3, Thyroid Hormone Receptor Interacting Protein 7, ThyroidReceptor-Interacting Protein 7, Thyroid Hor
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95% as determined by SDS-PAGE.
          Formulation
          HMGN3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH7.0) and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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