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HIF Prolyl Hydroxylases Rabbit mAb

HIF Prolyl Hydroxylases Rabbit mAb

Catalog Number:

A001549705RED

Mfr. No.:

RDSA66281

Price:

$470

Size:

100μL

Quantity:

Add to Cart:

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  A synthesized peptide derived from human HIF Prolyl Hydroxylases
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  
  Storage
  
  Store at -20°C. Avoid freeze / thaw cycles.
  
  Molecular Weight
  
  47kDa (Calculated)
  
  Antigen
  
  EGLN4 ;HIFPH4;Hypoxia inducible factor prolyl 4 hydroxylase;P4H with transmembrane domain;P4htm;PH4;PHD4;Proline 4 hydroxylase;Prolyl hydroxlase domain containing 4 (UniProt:Q9NXG6)
  
  * This product is for Research Use Only.

Applications

Application

WB; IHC; IP; FC

Application	Dilutions
WB	1:500-1:2000
IHC	1:50-1:200
IP	1:50
FC	1:50

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