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Overview
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Background
Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.
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- Properties
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Overview
HDAC6 Rabbit mAb
HDAC6 Rabbit mAb
Catalog Number:
A001550459RED
Mfr. No.:
RDSA67056
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.