GULP1 Recombinant Protein

GULP1 Recombinant Protein

Catalog Number:
P001415492ABE
Mfr. No.:
Abe32-3928
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • GULP1 Human Recombinant produced in E. coli is a single,non-glycosylated polypeptide chain containing 327 amino acids (1-304a.a) andhaving a molecular mass of 36.9kDa. GULP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. PTB domain-containing engulfment adapter protein 1 (GULP1) is an evolutionarily conserved adaptor protein essential for efficient phagocytosis of apoptotic cells by phagocytes. Furthermore, GULP1 helps modulate cellular glycosphingolipid and cholesterol transport. In addition, GULP1 may have a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP1 are linked with increases in cellular levels of GTP-bound ARF6.

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      • Properties
        • Protein Name
          GULP, Engulfment Adaptor PTB Domain Containing 1, PTBDomain Adapter Protein CED-6, Cell Death Protein 6 Homolog, CED6, GULP, PTB Domain Adaptor ProteinCED-6 Engulfment Adapter Protein, Protein GULP, CED-6.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greaterthan 95.0% as determined by SDS-PAGE.
          Formulation
          GULP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 50% glycerol and 2mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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