Name: H2AFZ Recombinant Protein
Price: Inquiry

- Overview
  - H2AFZ Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 151 amino acids (1-128 a.a) andhaving a molecular mass of 15.9kDa. H2AFZ is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HistoneH2A. Z (H2AFZ) belongs to the histone H2A family. Histones are basic nuclearproteins which are responsible for the nucleosome structure of the chromosomalfiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrappedaround a histone octamer composed of pairs of each of the four core histones(H2A, H2B, H3, and H4). H2AFZ is implicated in the formation of constitutiveheterochromatin and vital for chromosome segregation during cell division. Moreover, variant Histone H2A, which takes the place of conventional H2A in asubset of nucleosomes. Studies in mice have demonstrated that this particularhistone is essential for embryonic development and show that lack of functionalhistone H2A leads to embryonic lethality.
    
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- Properties
  - Protein Name
    
    H2A Histone Family, Member Z, H2AZ, H2A/z, H2A.Z-1, H2A.z, H2AZ Histone, Histone H2A.Z.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 85% as determined by SDS-PAGE.
    
    Formulation
    
    H2AFZ protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

H2AFZ Recombinant Protein

H2AFZ Recombinant Protein

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