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Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified TNFalpha

Coomassie-stained SDS-PAGE Lane 1: Molecular weight markers Lane 2: 5 µg purified TNFalpha

GST-TNFalpha

GST-TNFalpha

Catalog Number:

AN01097762UBP

Mfr. No.:

U1130

Price:

$440

Size:

50 µg

Quantity:

Add to Cart:

- Overview
  - TNFalpha (Tumor necrosis factor alpha) is produced by immune and epithelial cells. It plays important roles in regulating inflammation, apoptosis, and immune response. It exerts its function mainly by binding of two cell surface receptors TNFR1 and TNFR2. Treating cells with TNFalpha activates the NFkappaB, MAPK, and apoptotic signaling pathways. The recombinant GST-TNFalpha protein consists of a N-terminal GT tag with the C-terminal extracellular domain (amino acids 77-233) of full length TNFalpha. It can be used for pulldown assays. It binds TNFR1 and TNFR2 to induce downstream signaling pathways, but often requires higher concentrations than TNFalpha (catalog # U1120).
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    TNF; DIF; TNFA; TNFSF2; TNF-alpha
    
    Source
    
    Bacterial recombinant
    
    Formulation
    
    20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
    
    Storage
    
    Store at -80°C; avoid multiple freeze-thaw cycles
    
    Concentration
    
    See tube label
    
    Molecular Weight
    
    25.6 kDa
    
    Sequence
    
    NCBI RefSeq: NM_000594.3
    
    * Research Use Only

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