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Overview
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GPC4 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 165 amino acids (401-529a.a) andhaving a molecular mass of 18kDa. GPC4 is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glypican 4, also known as GPC4, is part of a family ofglycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans(HSPGs) which take part in the control of cell division and growth regulation. GPC4 is broadly expressed in human tissues, including lung, kidney, heart,placenta, skeletal muscle, and pancreas. In addition, GPC4 has been shown to bepresent in astrocytes, haematopoietic-progenitor and bone-marrow-stromal cells.
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Overview