Gentamicin C2a sulfate

Gentamicin C2a sulfate

Catalog Number:
A004187981BIO
Mfr. No.:
AG46305
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    • Overview
      • Gentamicin C2a sulfate is one epimeric form of the aminoglycoside antibiotic gentamicin (a.k.a. gentamycin). Gentamicin interferes with the correct protein production in bacterial cells, by binding to the 16s rRNA at the 30s ribosomal subunit. Gentamicin is a natural mixture of four congeners, one of which is gentamicin C2a. Gentamicin is active against clinically relevant aerobic gram-negative bacteria. Gentamicin C2a has been shown to be biodegradable in the environment, to some extent.

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    • Properties
      • Categories
        Antibiotics
        CAS Number
        157591-52-1
        Molecular Formula
        C20H41N5O7·xH2SO4
        Note
        There is no hazardous surcharge associated with this product.
        There is no special packaging charge associated with this product.

        * For research use only. Not for human or veterinary use

    • Reference
      • Gu et al (2015) Biosynthesis of Epimers C2 and C2a in the Gentamicin C Complex. Chembiochem: a European Journal of Chemical Biology 16(13):1933-1942.
        Liu et al (2017) Biodegradation of gentamicin by bacterial consortia AMQD4 in synthetic medium and raw gentamicin sewage. Scientific Reports 7:11004.
        Bulman et al (2020) Unraveling the Gentamicin Drug Product Complexity Reveals Variation in Microbiological Activities and Nephrotoxicity. Antimicrobial Agents and Chemotherapy 64(9):e00533-20.

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