Login / Register
0

GDC 0941

GDC 0941

Catalog Number:
L002236037BIO
Mfr. No.:
FI32904
Price:
Inquiry
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Enzyme Modulators
          Alternative Name
          2-(1H-Indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidine; Pictilisib
          CAS Number
          957054-30-7
          Molecular Formula
          C23H27N7O3S2
          Molecular Weight
          513.64 g/mol
          MDL Number
          MFCD11616196
          Note
          There is no hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference

        • Folkes et al (2008). The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer. Journal of Medicinal Chemistry, 51(18):5522-32.
          Raynaud et al (2009). Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941. Molecular Cancer Therapeutics, 8(7):1725-38.
          Hoeflich et al (2012). Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition. Cancer Research, 72(1):210-9.

    MSDS

    Documents

    Specification

    We Also Recommend

    17-Allylaminogeldanamycin

    17-Allylaminogeldanamycin

    BKM 120

    BKM 120

    BYL 719

    BYL 719

    Copanlisib

    Copanlisib

    Entinostat

    Entinostat

    Gefitinib

    Gefitinib

    Gefitinib

    Gefitinib

    $179

    Lapatinib base- Bio-X

    Lapatinib base- Bio-X

    Lapatinib ditosylate monohydrate

    Lapatinib ditosylate monohydrate

    Linsitinib

    Linsitinib

    $277

    Luminespib

    Luminespib

    MK 2206 dihydrochloride

    MK 2206 dihydrochloride

    Note: If you don't receive our verification email, do the following:

    • Confirm that you entered your email address correctly.
    • Check if the email is in your spam or junk folder.
    • Or you may contact us at .
    Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.