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Overview
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Gene Accession: NP002024
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Background
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Liver Lymphoma and Colon Adenocarcinoma. Among its related pathways are Mannose type O-glycan biosynthesis and Wnt / Hedgehog / Notch. GO annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. An important paralog of this gene is FUT5.
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