CDKL4 Polyclonal Antibody

CDKL4 Polyclonal Antibody

Catalog Number:
A001507456RED
Mfr. No.:
RD219685A
Price:
$253
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      • Overview
        • Calculated MW: 43 kDa
          Observed MW: Refer to figures
          Gene Accession: NP001009565

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          Background

          Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthetic peptide of human CDKL4
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.8 mg/mL
          Antigen
          CDKL4, CDKL4, Cyclin dependent kinase like 4, Cyclin-dependent kinase-like 4, EC 2.7.11.22, OTTHUMP00000164944 (UniProt:Q5MAI5)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:30-1:150
          ELISA 1:5000-1:10000

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