Follistatin, human recombinant protein

Please contact us at for specific academic pricing.

Background

Follistatin is a high-affinity activin-binding protein produced in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Follistatin acts as an activin antagonist whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). Follistatin also inhibits the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1.
The Human Follistatin cDNA encodes a 344 aa precursor protein with a 29 aa signal peptide. Recombinant human Follistatin is a 31.5 kDa protein containing 288 amino acids including 36 cysteine residues.