Name: FGFR4 Polyclonal Antibody (0.72 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: NP002002
  
  Please contact us at for specific academic pricing.
  
  Background
  
  The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthetic peptide of human FGFR4
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.72 mg/mL
  
  Antigen
  
  CD 334, CD334, CD334 antigen, fc13h 10, fc13h10, Fgfr 4, FGFR-4, Fgfr4, FGFR4, Fibroblast growth factor receptor 4, Hydroxyaryl protein kinase, JTK 2, JTK2, MGC20292, Protein tyrosine kinase, TKF, Tyrosine kinase related to fibroblast growth factor receptor, Tyrosylprotein kinase (UniProt:P22455)
  
  * For reference only.

Applications

Application

IHC; ELISA

Application	Dilutions
IHC	1:10-1:50
ELISA	1:5000-1:10000

FGFR4 Polyclonal Antibody (0.72 mg/mL) for IHC, ELISA

FGFR4 Polyclonal Antibody (0.72 mg/mL) for IHC, ELISA

Background

We Also Recommend

BAG2 Polyclonal Antibody (0.9 mg/mL) for WB, IHC, ELISA

DCX Polyclonal Antibody (1.3 mg/mL) for WB, IHC, ELISA

PPP1R15A Polyclonal Antibody (1.8 mg/mL) for IHC, ELISA