Name: DCX Polyclonal Antibody (1.3 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 49 kDa
  Observed MW: Refer to figures
  Gene Accession: NP000546
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Synthetic peptide of human DCX
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.3 mg/mL
  
  Antigen
  
  DBCN, Dbct, DC, DCX, DCX, Doublecortex, Doublin, FLJ51296, Lis X, Lis-X, Lissencephalin X, Lissencephalin-X, Lissencephaly X linked, Lissencephaly X linked doublecortin, LISX, Neuronal migration protein doublecortin, OTTHUMP00000023859, OTTHUMP00000023860, OTTHUMP00000216315, OTTHUMP00000216316, SCLH, XLIS (UniProt:O43602)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:25-1:100
ELISA	1:5000-1:10000

DCX Polyclonal Antibody (1.3 mg/mL) for WB, IHC, ELISA

DCX Polyclonal Antibody (1.3 mg/mL) for WB, IHC, ELISA

Background

We Also Recommend

DDC Polyclonal Antibody (1.5 mg/mL) for WB, IHC, ELISA

GRM2 Polyclonal Antibody (1.5 mg/mL) for IHC, ELISA

MORF4L1 Polyclonal Antibody (1.1 mg/mL) for WB, IHC, ELISA