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Overview
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Background
Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766.
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Overview
FGFR1 Rabbit mAb
FGFR1 Rabbit mAb
Catalog Number:
A001550230RED
Mfr. No.:
RDSA66827
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.