FGF10-STAB® Thermostable FGF10

Thermostable FGF10 for research use
Patent pending – WO2023089157A1

Competitive advantage:
FGF10 is a mesenchymal signaling molecule and a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes – embryonic development, cell growth, morphogenesis and tissue repair. Thermostable form of FGF10 – FGF10-STAB® – has significantly improved half-life at 37°C and fully retained biological activity. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies have suggested that FGF10 gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation.

· Longer biological activity
Densitometric characterization of ERK phorsphorylation in MCF7 cells
· Much lower dosage needed
4MBr-5 cell proliferation was tested after preincubation at 37°C for 7 days
· Longer digestion half-life
Densitometric characterization of degradation by trypsin
· Thermal stability increased by 18°C
· Animal-free product

Organism: Human

Please contact us at for specific academic pricing.