Extracellular OCR Plate Assay Kit

Applicable to regular fluorescent plate reader with temperature-controlled incubation
No need for an expensive instrument, special medium, and plates
All-in-One Kit with OCR calculation Sheets

OCR is an Important Indicator for Mitochondrial Function
Since oxygen is consumed mainly in the process of adenosine triphosphate (ATP) production by mitochondrial oxidative phosphorylation, its oxygen consumption rate (OCR) is an indicator for the analysis of mitochondrial function. It is known that cancer cells produce ATP using the glycolytic pathway, which is less efficient than oxidative phosphorylation. It is also known that in immune cells, the predominance of oxidative phosphorylation inhibits anti-tumor effects, whereas the predominance of the glycolytic pathway promotes anti-tumor effects. As an indicator of their energy metabolism, the OCR of cells has been measured.

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