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Overview
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Background
This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation.
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Overview
ErbB3 (HER3) Rabbit mAb
ErbB3 (HER3) Rabbit mAb
Catalog Number:
A001550019RED
Mfr. No.:
RDSA66617
Price:
$470
Size:
100μL
Quantity:
Add to Cart:
.