Enramycin

Enramycin

Catalog Number:
M001342309TOK
Mfr. No.:
TOK-E006
Price:
$318
  • Size:
    10 mg
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Enramycin acts as a MurG inhibitor involved in peptidoglycan synthesis in Gram-positive bacteria. MurG catalyzes the transglycosylation reaction in the final step of peptidoglycan biosynthesis. Inhibition of this step greatly compromises cell wall integrity leading to cell lysis.

      • Properties
        • CAS Number
          11115-82-5
          Molecular Formula
          Enramycin A: C107H138Cl2N26O31
          Enramycin B: C108H140Cl2N26O31
          Molecular Weight
          Enramycin A: 2550.21
          Appearance
          Light tan powder
          Solubility
          Acids (Dilute HCl): Freely soluble Dimethylformamide: Freely soluble Water: Slightly soluble
          Other Properties
          Source: Streptomyces fungicidus
          Purity Level: (HPLC, As Is): ≥95.0%
          Storage
          -20°C

          * For research use only

      • Applications
        • Application Description
          Spectrum: Enramycin has strong antibacterial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and inhibits the development of major gut flora pathogens. Resistance or cross-resistance with existing antibiotics has rarely been observed.

          Microbiology Applications: Enramycin is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive microbial isolates. Medical microbiologists use this information to recommend antibiotic treatment options.

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