Endothelin Receptor type B - ExpressMAX™ Human GPCR ORF Clones

Endothelin Receptor type B - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268628CAN
Mfr. No.:
G0548-B; G0548-Plus
Price:
$573
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      • Overview
        • Endothelin Receptor type B is a member of the GPCR family, encoded in Humans by the EDNRB gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene and it exhibit different responses upon binding. Mutations in this gene cause Hirschsprung disease type 2 and in melanocytic cells, the mutated EDNRB gene is linked to Waadenburg syndrome. It activates a phosphatidylinositol-calcium second messenger system.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Human GPCR ORF Clones
          Other Properties
          Plasmid size: 6881 bp
          Promoter: pCMV
          ORF Sequence (GenBank based): NM_000115.3
          Protein Sequence (SwissProt): P24530
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: ETB, ET-B, ETB1 or ETBR
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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