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Overview
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Endothelin Receptor type B is a member of the GPCR family, encoded in Humans by the EDNRB gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene and it exhibit different responses upon binding. Mutations in this gene cause Hirschsprung disease type 2 and in melanocytic cells, the mutated EDNRB gene is linked to Waadenburg syndrome. It activates a phosphatidylinositol-calcium second messenger system.
Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.Please contact us at for specific academic pricing.
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- Properties
- Applications
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Overview