Apelin Receptor - ExpressMAX™ Human GPCR ORF Clones

Apelin Receptor (APLNR, APJ) is a GPCR with considerable sequence homology to the angiotensin Receptor, which is actually an apelin Receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. Its predominant endogenous ligands are apelin-36, apelin-13 and [Pyr1]-apelin-13. APLNR Receptor and apelin peptides act as mediators of cardiovascular and Central Nervous System functions, fluid homeostasis, adipocyte endocrine secretion, glucose metabolism, in embryonic and tumor angiogenesis and as a HIV-1 co-receptor.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

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