Elaiophylin

Elaiophylin

Catalog Number:
FC01365594APE
Mfr. No.:
APE-B2138
Price:
$265
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Elaiophylin shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.

      • Properties
        • Categories
          macrodiolide antibiotic
          Alternative Name
          (3E,5E,7S,8S,11E,13E,15S,16S)-8,16-bis[(2S,3R,4S)-4-[(2R,4R,5R,6R)-4-[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-ethyl-2-hydroxy-6-methyloxan-2-yl]-3-hydroxypentan-2-yl]-7,15-dimethyl-1,9-dioxacyclohexadeca-3,5,11,13-tetraene-2,10-dione
          CAS Number
          37318-06-2
          Molecular Formula
          C54H88O18
          Molecular Weight
          1025.27
          Appearance
          A white powder
          Purity
          Purity ≥95.00%
          Solubility
          Soluble in DMSO
          Storage
          Store at -20°C
          SMILES
          CCC1C(OC(CC1OC2CC(C(C(O2)C)O)O)(C(C)C(C(C)C3C(C=CC=CC(=O)OC(C(C=CC=CC(=O)O3)C)C(C)C(C(C)C4(CC(C(C(O4)C)CC)OC5CC(C(C(O5)C)O)O)O)O)C)O)O)C

          * For Research Use Only

      • Reference
        • 1. Jianwei Zheng, Junfeng Wang, et al. "Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin." Acta Pharmaceutica Sinica B, Available online 12 July 2020.

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