Dopamine Receptor D2 - ExpressMAX™ Human GPCR ORF Clones

Dopamine Receptor D2 - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268626CAN
Mfr. No.:
G0546-B; G0546-Plus
Price:
$573
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      • Overview
        • Dopamine Receptor D2 is a member of the GPCR family and it is encoded in Humans by the DRD2 gene. Alternative splicing of this gene results in two different isoforms. There is a third form but it is not known whether it is actually a splicing aberration or a normal form. A missense mutation in this gene causes myoclonus dystonia and others mutations have been associated with schizophrenia. It inhibits adenylyl cyclase activity. Regulating the expression of this receptor in mice, controls synaptic plasticity, memory and exploration.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Human GPCR ORF Clones
          Other Properties
          Plasmid size: 7376 bp
          Promoter: pEF1a
          ORF Sequence (GenBank based): NM_000795.3
          Protein Sequence (SwissProt): P14416
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: D2R or D2DR
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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