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Overview
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DNase I is a recombinant endonuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, to release di-, tri- and oligonucleotide products (on average producing tetranucleotides) with 5’-phosphorylated and 3’-hydroxylated ends. It acts on single-stranded DNA, double-stranded DNA, RNA-DNA hybrids and chromatin. DNase I requires bivalent cations (Mg2⁺ and Ca2⁺) for maximal activity. GMP-grade reagent also available. Learn more.
Includes :
– 1 mL DNase I (10 mg/mL)
– 1 mL Reaction Buffer (10x)Please contact us at for specific academic pricing.
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- Properties
- Applications
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Overview