DMT-Cholesterol (Plant) TEG CE phosphoramidite

DMT-Cholesterol (Plant) TEG CE phosphoramidite

Catalog Number:
NAS1056420CHE
Mfr. No.:
CLP-2794
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      • Overview

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      • Properties
        • Categories
          Cholesterol Amidites and Supports
          Molecular Formula
          C70H106N3O11P
          Molecular Weight
          1196.580
      • Applications
        • Application Description
          Cholesteryl TEG phosphoramidite and solid supports:

          Potential therapeutic oligonucleotides must permeate the cell membrane for optimal activity. The addition of lipophilic groups such as Cholesteryl to an oligonucleotide would be expected to enhance this activity. The use of Cholesteryl oligos and the consequent improvement in activity has been described. Cholesteryl phosphoramidite is designed with branched tetra-ethylene-glycol (TEG) spacer for maximum solubility in acetonitrile as well as for applications requiring multiple labels.

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