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Overview
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N-(2-Methoxy-2-oxoacetyl)glycine methyl ester; Dimethyloxalylglycine
DMOG inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1a and inhibiting JMJD2A (IC50 = 2.5 mM). Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation. Prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage.Please contact us at for specific academic pricing.
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Overview