Discodermolide

Discodermolide

Catalog Number:
I001579827DCC
Mfr. No.:
DC80547
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    • Overview
      • Discodermolide (NVP-XAA-296) is a potent microtubule-stabilizing agent with a Ki of 0.4 μM. Discodermolide stabilizes microtubules, induces G2 or M phase cell cycle arrest and apoptosis, leading to inhibition of cancer cell proliferation. Discodermolide competitively inhibits the binding of Paclitaxel to tubulin polymers, and inhibits the growth of Paclitaxel-resistant cells. Discodermolide can be used for breast and colon cancer research.

        Please contact us at for specific academic pricing.

    • Properties
      • Alternative Name
        ALAPYIP
        CAS Number
        1260529-82-5
        Molecular Formula
        C37H57N7O9
        Molecular Weight
        743.89
        Storage
        2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
        SMILES
        O=C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)[C@H](C)N

        * For Research Use Only.

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