DHR 123 [Dihydrorhodamine 123]

DHR 123 [Dihydrorhodamine 123]

Catalog Number:
CSA1277403ABP
Mfr. No.:
ABPB_C261
Price:
$360
  • Size:
    10 mg
    Quantity:
    Add to Cart:
      • Overview
        • Dihydrorhodamine 123 is the reduced form of rhodamine 123, which is a commonly used fluorescent mitochondrial dye. Dihydrorhodamine 123 itself is non-fluorescent, but it readily enters most of the cells and is oxidized by oxidative species or by cellular redox systems to the fluorescent rhodamine 123 that accumulates in mitochondrial membranes. Dihydrorhodamine 123 is useful for detecting reactive oxygen species including superoxide and peroxynitrite.

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          More Details

      • Properties
        • Categories
          Mitochondria stains
          Molecular Weight
          346.38
          Other Properties
          Excitation/Emission (nm): 505/534 (oxidized form)
          Storage
          -20°C, protect from light
          Shipping
          Ice pack

          * For research use only

      • Applications
        • Application
          Mitochondria labeling
      • Reference
        • Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. Reiter CD, Teng RJ, Beckman JS, J Biol Chem (2000) 275:32460-32466
          Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivo. Jourd'heuil D, Jourd'heuil FL, Kutchukian PS, Musah RA, Wink DA, Grisham MB, J Biol Chem (2001) 276:28799-28805
          Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide. Miles AM, Bohle DS, Glassbrenner PA, Hansert B, Wink DA, Grisham MB, J Biol Chem (1996) 271:40-47

    Documents

    Protocol-C261

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