Desthiobiotin-PEG3-NHS ester

Desthiobiotin-PEG3-NHS ester

Catalog Number:
PG01492653ALA
Mfr. No.:
D597253-100mg; D597253-250mg; D597253-500mg
Price:
$1,262
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    • Overview
      • Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.

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    • Properties
      • CAS Number
        2411681-92-8
        Molecular Formula
        C23H38N4O9
        Molecular Weight
        514.6
        Purity
        98%
        Other Properties
        Solubility: Solubility in Water, DMSO, DCM, DMF
        Storage
        Store at -20°C
        Shipping
        Dry ice

        * For research use only. Not for use in human or animal.