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Overview
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Density marker beads are small colored microspheres of known mass density that are used for calibrating density gradients and determining density in gradient columns. Density gradients are often used for separations and purification of cells, viruses and sub-cellular particles. Generally a set of several density marker beads covering a range of densities is used. The gradient is calibrated with beads that float at different heights within the column. When a test sample is added to the column it drops until the point of neutral buoyancy and the density is determined from the calibration chart. Density gradient columns can be used to measure the density of any sample.
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Overview