CyFlow™ MPO Purified

CyFlow™ MPO Purified

Catalog Number:
A001344220SYS
Mfr. No.:
CR212947
Price:
$306
  • Size:
    0.1 mg (0.1 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          MPO421-8B2
          Immunogen
          Human myeloperoxidase
          Conjugate
          Purified
          Formulation
          The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Concentration
          1 mg/mL
          Regulatory Status
          RUO

          * Research use only

      • Applications
        • Application
          ELISA; Flow Cytometry

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