CyFlow™ MPO FITC

CyFlow™ MPO FITC

Catalog Number:
A001344222SYS
Mfr. No.:
CN934321
Price:
$456
  • Size:
    100 tests (0.4 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human
          Clone
          MPO421-8B2
          Immunogen
          Human myeloperoxidase
          Conjugate
          FITC
          Formulation
          The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Regulatory Status
          RUO

          * Research use only

      • Applications
        • Application
          Flow Cytometry
          Application Description
          The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

          Emission Maximum: 518 nm
          Excitation Maximum: 490 to 495 nm

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