Name: CXCL9(74-103)
Price: 397.00 USD

- Overview
  - Competes with CXCL8 for GAG binding.
    CXCL9(74-103) is a peptide corresponding to the C-terminal amino acids of the chemokine CXCL9. ? CXCL9(74-103) does not signal through or act as an antagonist for CXCR3, the CXCL9 receptor, or influence the neutrophil chemotactic activity of CXCL8 in vitro, but it does display high affinity for glycosaminoglycans (GAGs), and can displace chemokines bound to GAGs. CXCL8 and CXCL9 drive leukocyte migration to inflammation sites and through this inhibition of the chemokine-GAG interaction, CXCL9(74-103) can block neutrophil migration. In vivo, CXCL9(74-103) ameliorates joint inflammation in a murine model of antigen induced arthritis, reducing neutrophil accumulation and joint and cartilage damage, and is also effective in a murine model of gout.
    
    Please contact us for availability.
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Peptides
    
    Alternative Name
    
    CXCL9 peptide
    
    Molecular Formula
    
    C158H295N59O40
    
    Molecular Weight
    
    3659.29
    
    Appearance
    
    Freeze dried solid
    
    Purity
    
    >95% by HPLC
    
    Solubility
    
    Soluble in water
    
    Other Properties
    
    Sequence: H-Lys-Lys-Lys-Gln-Lys-Asn-Gly-Lys-Lys-His-Gln-Lys-Lys-Lys-Val-Leu-Lys-Val-Arg-Lys-Ser-Gln-Arg-Ser-Arg-Gln-Lys-Lys-Thr-Thr-OH,KKKQKNGKKHQKKKVLKVRKSQRSRQKKTT
    
    Storage
    
    Store dry, frozen and in the dark
    
    * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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