Name: Cromolyn sodium
Price: 145.00 USD

- Overview
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    Background
    
    Cromolyn sodium is a stabilizer of mast cell membrane [1].Cromolyn sodium has been used to treat for asthma for many years. It is a derivative of khellin and is proved to be a unique antiallergic agent. The prior administration of cromolyn sodium inhibits allergen-induced histamine release in the animal experiments. Because the oral absorption of cromolyn sodium is minimal and only the powder form of it is available, cromolyn sodium is usually used through being inhaled from a special apparatus. Cromolyn sodium can suppress both immediate and late-onset asthmatic responses and suppress the release of NCF-A. It also inhibits the impairment of mucociliary transport induced by specific bronchial challenge. Moreover, cromolyn sodium also ameliorates exercise-induced asthma [1].
    
    [1] Bernstein I L. Cromolyn sodium. CHEST Journal, 1985, 87(1_Supplement): 68S-73S.
- Properties
  - Categories
    
    Mast cell membrane stabilizer
    
    Alternative Name
    
    disodium;5-[3-(2-carboxylato-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylate
    
    CAS Number
    
    15826-37-6
    
    Molecular Formula
    
    C23H14Na2O11
    
    Molecular Weight
    
    512.33
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in EtOH; insoluble in H2O; ≥5.12 mg/mL in DMSO
    
    Storage
    
    Desiccate at -20°C
    
    SMILES
    
    C1=CC2=C(C(=C1)OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)[O-])O)C(=O)C=C(O2)C(=O)[O-].[Na+].[Na+]
    
    * For Research Use Only