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Overview
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MITF-A is an isoform of MITF (microphthalmia-associated transcription factor), a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.This lentivirus expresses human MITF-A under the control of the CMV promoter.
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Overview
CMV-MITF-A lentivirus
CMV-MITF-A lentivirus
Catalog Number:
PLP1516148CEL
Mfr. No.:
PLV-10087-50/200
Price:
$945
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