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Cholesterol phosphoramidite

Cholesterol phosphoramidite

Catalog Number:
CAL1278200APT
Mfr. No.:
APT-1125
Price:
$307
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      • Overview

        • Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Cholesterol phosphoramidite
          Alternative Name
          (1S,2R,5S,10S,11S,14R,15R)-2,15‐dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.02,7.011,15]heptadec‐7‐en‐5‐yl N‐{6‐[(2S,4R)‐2‐{[bis(4‐methoxyphenyl)(phenyl)methoxy]methyl}‐4‐({[bis(propan‐2‐yl)amino](2‐cyanoethoxy)phosphanyl}oxy)pyrrolidin‐1‐yl]‐6‐oxohexyl}carbamate
          Molecular Formula
          C69H101N4O8P
          Molecular Weight
          1145.6 g/mol
          Appearance
          White foam
          Other Properties
          1H NMR (CD3CN): Conforms to the internal standard
          31P NMR (CD3CN): Conforms to the internal standard
          Assay: ≥99% (NMR)
          Storage
          Keep in a dark and dry place at -20°C (Shelf Life: 1 year)

          * Research Use Only

      • Applications
        • Application Description
          Dilution: dilute 100 mg of Cholesterol phosphoramidite Pro in
          0.87 mL of 10% THF in anhydrous acetonitrile to obtain 0.1M solution. Swirl occasionally over several minutes until product is completely dissolved

          Oxidation: standard iodine solution

          Coupling: 15 minute coupling time

          Deprotection: cleave and deprotect as required by nucleobases

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