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Cholesterol phosphoramidite

Cholesterol phosphoramidite

Catalog Number:

CAL1278200APT

Mfr. No.:

APT-1125

Price:

$315

Size:

Quantity:

Add to Cart:

- Overview
  - Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Cholesterol phosphoramidite
    
    Alternative Name
    
    (1S,2R,5S,10S,11S,14R,15R)-2,15‐dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.02,7.011,15]heptadec‐7‐en‐5‐yl N‐{6‐[(2S,4R)‐2‐{[bis(4‐methoxyphenyl)(phenyl)methoxy]methyl}‐4‐({[bis(propan‐2‐yl)amino](2‐cyanoethoxy)phosphanyl}oxy)pyrrolidin‐1‐yl]‐6‐oxohexyl}carbamate
    
    Molecular Formula
    
    C69H101N4O8P
    
    Molecular Weight
    
    1145.6 g/mol
    
    Appearance
    
    White foam
    
    Other Properties
    
    1H NMR (CD3CN): Conforms to the internal standard
    31P NMR (CD3CN): Conforms to the internal standard
    Assay: ≥99% (NMR)
    
    Storage
    
    Keep in a dark and dry place at -20°C (Shelf Life: 1 year)
    
    * Research Use Only
- Applications
  - Application Description
    
    Dilution: dilute 100 mg of Cholesterol phosphoramidite Pro in
    0.87 mL of 10% THF in anhydrous acetonitrile to obtain 0.1M solution. Swirl occasionally over several minutes until product is completely dissolved
    
    Oxidation: standard iodine solution
    
    Coupling: 15 minute coupling time
    
    Deprotection: cleave and deprotect as required by nucleobases

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