cfDNA Special A Cf-DNA Extraction Cell Free DNA Extraction

Cell-free DNA (cfDNA) refers to short, fragmented DNA molecules that are released into the bloodstream and other bodily fluids following cell death (apoptosis or necrosis). These fragments, typically ranging from 160 to 200 base pairs in length, provide a non-invasive window into the physiological and pathological state of the body.
Our cell-free DNA (cfDNA) Extraction Magnetic Beads are engineered for the highly efficient and reliable isolation of short-fragment, low-concentration cfDNA from plasma, serum, and other liquid biopsies. Utilizing a specialized surface chemistry, these beads demonstrate superior binding affinity for dsDNA and ssDNA across a wide size range, ensuring maximum recovery of the critical 160-180 bp fraction that is rich in biological information. This technology is the cornerstone for robust and reproducible liquid biopsy workflows, enabling downstream applications in non-invasive prenatal testing (NIPT), cancer early detection, and transplant monitoring.

Key Features & Advantages:
· Optimized for Short Fragments: Superior recovery efficiency for short, fragmented cfDNA, minimizing the loss of critical biomarkers.
· High Sensitivity & Yield: Designed for maximum yield from low-input and low-concentration samples, which is essential for liquid biopsy applications.
· Exceptional Purity: Effectively removes contaminants such as proteins, salts, and cellular genomic DNA, providing clean cfDNA ideal for sensitive downstream assays like NGS and dPCR.
· Robust & Automation-Ready: Exhibits excellent chemical stability and dispersion, ensuring batch-to-batch consistency and seamless integration into automated, high-throughput nucleic acid extraction systems.
· Rapid Workflow: Streamlines the extraction process, reducing hands-on time and enabling quick turnaround from sample to analysis.
This product is an indispensable tool for clinical researchers and diagnostic developers who require the highest standards of performance in their cfDNA analysis pipeline.

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