Cetrorelix

- Overview
  - Cetrorelix dicetate (SB-75) is a novel, potent and synthetic gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. Cetrorelix acetate is a decapeptide with the potential to be used in infertility treatment. The expression of GnRH (GnRH-I, LHRH) and its receptor as a part of an autocrine regulatory system of cell proliferation has been demonstrated in a number of human malignant tumors, including cancers of the ovary. The proliferation of human ovarian cancer cell lines is time- and dose-dependently reduced by GnRH and its superagonistic analogs.
    
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- Properties
  - Categories
    
    Peptides
    
    CAS Number
    
    120287-85-6
    
    Molecular Formula
    
    C70H92CLN17O14
    
    Molecular Weight
    
    1431.06
    
    Purity
    
    ≥98%
    
    Storage
    
    Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
    In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
    
    Shipping
    
    Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
    
    SMILES
    
    C[C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@H](NC([C@H](NC(C)=O)CC2=CC=C3C=CC=CC3=C2)=O)CC4=CC=C(C=C4)Cl)=O)CC5=CC=CN=C5)=O)CO)=O)CC6=CC=C(C=C6)O)=O)CCCNC(N)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)=O)C(N)=O
    
    * For research use only

Cetrorelix

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