Cetrorelix diacetate (SB 75)

Cetrorelix diacetate (SB 75)

Catalog Number:
P004439873INV
Mfr. No.:
V34641
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      • Overview
        • Cetrorelix dicetate (SB-75) is a novel, potent and synthetic gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. Cetrorelix acetate is a decapeptide with the potential to be used in infertility treatment. The expression of GnRH (GnRH-I, LHRH) and its receptor as a part of an autocrine regulatory system of cell proliferation has been demonstrated in a number of human malignant tumors, including cancers of the ovary. The proliferation of human ovarian cancer cell lines is time- and dose-dependently reduced by GnRH and its superagonistic analogs.

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      • Properties
        • Categories
          Peptides
          CAS Number
          130143-01-0
          Molecular Formula
          C70H92CLN17O14.2(C2H4O2)
          Molecular Weight
          1551.16
          Purity
          ≥98%
          Storage
          Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
          In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
          Shipping
          Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
          SMILES
          NC(NCCCCC(N1[C@H](C(N([C@H](C)C(N(C([C@H](N)CC2=CC=C(Cl)C=C2)=O)C([C@H](CC2=CC=C(OC(C)=O)C=C2)NC([C@H](COC(C)=O)NC([C@H](N)CC2=CN=CC=C2)=O)=O)=O)=O)C([C@H](NC(C)=O)CC2=CC3=CC=CC=C3C=C2)=O)=O)CCC1)=O)=N

          * For research use only

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