Cetirizine

Cetirizine

Catalog Number:

FC01364834APE

Mfr. No.:

APE-A3298

Price:

$180

Size:

100mg

Quantity:

Add to Cart:

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. Cetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. found that it inhibited the expression of VCAM-1 in patients with atopic dermatitis. The levorotary enantiomer of cetirizine, known as levocetirizine, is the more active form. From Wikipedia.
- Properties
  - Categories
    
    Antihistamine
    
    Alternative Name
    
    2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
    
    CAS Number
    
    83881-51-0
    
    Molecular Formula
    
    C21H25ClN2O3
    
    Molecular Weight
    
    388.89
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in EtOH; ≥122 mg/mL in H2O; ≥19.44 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

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