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Overview
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Cecropin P1, porcine is the first of the cecropin family to be isolated from a mammal rather than an insect. It has garnered a lot of interest for its antiviral and broad-spectrum antibacterial activities. It is also active against fungi, and has cytotoxic effects on cancer cell lines.
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Background
The antibacterial mode of action for Cecropin P1 is referred to as a "carpet-like" mechanism, in which the charged antimicrobial aligns on the outside of the cell's membrane and destabilizes the packing of the lipid bilayer, eventually causing the membrane to break down.
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Overview
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