Name: CDH12 Polyclonal Antibody (1.74 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: NP004052
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Synthetic peptide of human CDH12
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.74 mg/mL
  
  Antigen
  
  Br cadherin, BR-cadherin, Brain cadherin, CAD12_HUMAN, cadherin 12 (N cadherin 2), Cadherin 12, Cadherin 12 precursor, Cadherin 12 type 2 (N cadherin 2), Cadherin 12 type 2, Cadherin neural type 2, Cadherin-12, CDH12, CDHB, FLJ34857, N cadherin 2, N-cadherin 2, Neural type cadherin 2, Neuronal cadherin 2 (UniProt:P55289)
  
  * For reference only.