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Overview
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Inhibits nicotine-induced catecholamine release.
Catestatin (human) is a neuroendocrine peptide that is derived from proteolytic cleavage of the precursor chromogranin A, corresponding to fragments 352-372 of human chromogranin A. Catestatin (human) was first identified as a potent inhibitor of nicotine-induced catecholamine release and as it is secreted together with catecholamines, it can function as an autocrine negative feedback-loop. Catestatin (human) also plays a role in the regulation of hypertension and cardiac function, as well as in promoting angiogenesis, decreasing obesity and regulating innate immunity.
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Overview