Name: Caspase 9 cleaved Asp330 Antibody
Price: 180.00 USD

Overview
- Sensitivity: Endogenous
  Target name: Caspase 9 cleaved Asp330
  Area: Apoptosis / Caspase
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Properties
- Host
  
  Rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  Human
  
  Clone
  
  pAb
  
  Immunogen
  
  Synthetic peptide corresponding to residues surrounding Asp330 of human Caspase 9
  
  Storage
  
  Store at +4°C for short term storage. Long time storage is recommended at -20°C
  100mM Tris Glycine, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
  
  Molecular Weight
  
  45, 33, 37, 39
  
  * For research use only.