Cannabinoid 2 Receptor - ExpressMAX™ Human GPCR ORF Clones

Cannabinoid 2 Receptor inhibits adenylate cyclase activity through their Gi/Gαo subunits in a dose dependent for its ligand. The principal endogenous ligand for the CNR2 receptor is 2-archidonoylglycerol. Through their Gβϒ subunits, CNR2 Receptor is coupled to the MAPK-ERK pathway, which regulates cellular processes in both mature and developing tissues. It is localized on immune cells such as monocytes, macrophages, B-cells and T-cells. It is also found in the brain, on microglia but not in neurons and the gastrointestinal system, where it modulates intestinal inflammatory response.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

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