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Overview
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4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
C-646 is a potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM )1. Induces apoptosis in prostate cancer cells2. Enhances fear extinction memory and synaptic plasticity in mice3. Promotes tau deacetylation reducing levels of pathogenic p-tau4. Cell permeable.Please contact us at for specific academic pricing.
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