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C-646

C-646

Catalog Number:

I001528147REA

Mfr. No.:

EI-HAT-001

Price:

$306

Size:

5 mg

Quantity:

Add to Cart:

- Overview
  - 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
    
    C-646 is a potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM )1. Induces apoptosis in prostate cancer cells2. Enhances fear extinction memory and synaptic plasticity in mice3. Promotes tau deacetylation reducing levels of pathogenic p-tau4. Cell permeable.
    
    Please contact us at for specific academic pricing.
- Properties
  - Molecular Formula
    
    C24H19N3O6
    
    Molecular Weight
    
    MW=445.4
    
    Appearance
    
    Orange powder
    
    Solubility
    
    Solubilization: May be dissolved in DMSO (10 mg/ml)
    
    Storage
    
    Store desiccated as supplied at 4°C for up to 2 years. Store solutions at -20°C for up to 2 months.
    
    * For Research Use Only.
- Applications
  - Application
    
    Epigenetic Inhibitors

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