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Overview
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BX-795 is an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1), as well as other kinases including TANK-binding kinase 1 (TBK1), Aurora B and IkB kinase ε (IKKε). BX-795 prevents TBK1- and IKKε-mediated activation of IRF3 and production of IFN-β.
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Overview